Your Next Dose: July 2023 Edition

This month in virus & vaccine news…

We’re seeing some worrisome trends regarding childhood immunizations. There was plenty of concern about this during height of the pandemic. The Director-General of the World Health Organization is encouraged by increasing childhood vaccinations in some countries, but almost 50% of countries that saw declines are not improving, according to the United Nations. The US is still grappling with kids being behind on vaccines, too.

Some ongoing outbreaks in the United States:

CDC might start recommending annual COVID boosters similar to the annual influenza vaccine recommendation, and respiratory syncytial virus (RSV) for some age groups. The flu vaccine has been around for a long time, and the COVID vaccine is a recent but pervasive development. However, the RSV vaccines are new. Arexvy (GSK) and ABRYSVO (Pfizer) were both approved for use in adults aged 60 and older by the US Federal Drug Administration in May of this year. The CDC has also recommended these vaccines for the same age group. And there is some press around a possible “Tripledemic” of COVID, flu, and RSV in the fall to winter, so we’ll see how the conversation around the RSV vaccine, and an annual COVID shot for that matter, evolves as summer comes to an end.

National Institutes of Health

July 17: Construction of Recombinant Baculoviruses Carrying the Gene Encoding the Major Capsid Protein, VP1, From Calicivirus Strains (Including Norovirus Strains Toronto, Hawaii, Desert Shield, Snow Mountain, and MD145-12)

July 17: Construction of an Infectious Full-Length cDNA Clone of the Porcine Enteric Calicivirus RNA Genome

July 17: Enzymatically-Active RNA-Dependent RNA Polymerase From a Human Norovirus (Calicivirus)

July 17: Full-Length cDNA Clone Representing the Consensus Sequence of the RNA Genome of a Human Norovirus (strain MD145-12) That Encodes Biologically Active Proteins

July 24: Codon Deoptimized (CD) Poliovirus Seed Strains for Use in an Inactivated Poliovirus Vaccine

July 29: Codon Deoptimized (CD) Poliovirus Seed Strains for Use in an Inactivated Poliovirus Vaccine

July 30: Codon Deoptimized (CD) Poliovirus Seed Strains for Use in an Inactivated Poliovirus Vaccine

July 31: Codon Deoptimized (CD) Poliovirus Seed Strains for Use in an Inactivated Poliovirus Vaccine

July 31: Hybridomas Producing Antibodies to Neuraminidase for Influenza A (H3N2) Diagnostics, Vaccine, and Therapeutic Development

July 31: New Cholera Vaccine and Method for Conjugating Bacterial Polysaccharides to Proteins

July 31: Modified Peptide Nucleic Acids (PNAs) for Detection of DNA or RNA and Identification of a Disease or Pathogen

July 31: Replicating RNA Vaccine For Crimean-Congo Hemorrhagic Fever Virus

July 31: Modified Bacterial Strain for Otitis Media Vaccine

July 31: Anti-Plasmodium Compositions and Methods of Use